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    已发表论文

    用于细胞成像的叶酸氮化碳点微波辅助多元醇的合成

     

    Authors Guan WW, Gu W, Ye L, Guo CY, Su S, Xu PX, Xue M

    Published Date October 2014 Volume 2014:9(1) Pages 5071—5078

    DOI http://dx.doi.org/10.2147/IJN.S68575

    Received 29 May 2014, Accepted 27 August 2014, Published 31 October 2014

    Approved for publication by Professor Thomas J. Webster

    Abstract: A green, one-step microwave-assisted polyol synthesis was employed to prepare blue luminescent carbon nitride dots (CNDs) using folic acid molecules as both carbon and nitrogen sources. The as-prepared CNDs had an average size of around 4.51 nm and could be well dispersed in water. Under excitation at 360 nm, the CNDs exhibited a strong blue luminescence and the quantum yield was estimated to be 18.9%, which is greater than that of other reported CNDs. Moreover, the CNDs showed low cytotoxicity and could efficiently label C6 glioma cells, demonstrating their potential in cell imaging.
    Keywords: carbon nitride dots (CNDs), folic acid, photoluminescence, cell imaging






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