Zhili Yang, Jiejie Lu, Zhen Li

Department of Dermatology, The Fifth People’s Hospital of Hainan Province, Haikou, Hainan, People’s Republic of China

Correspondence: Zhen Li, Email nanji9207@163.com Jiejie Lu, Email lujiejie677@163.com

Abstract: Generalized Pustular Psoriasis (GPP) is a recurrent dermatological condition characterized by widespread erythematous plaques, scaling, and sterile pustules. Notably, in a subset of patients, these lesions manifest exclusively in localized areas. We report a case where abrocitinib was used to treat the localized type of GPP, achieving relatively good clinical efficacy and without obvious side effects. To date, there are no published reports on the use of abrocitinib for GPP treatment, either domestically or internationally, making this case a valuable reference for clinicians and researchers.

Keywords: generalized pustular psoriasis, abrocitinib, JAK inhibitor