Fan Xu,1 Xiaoli Zhong,2 Qiao Li,1 Xi Luo,1 Na Wang,1 Jing Wang,1 Shaoju Xie,1 Jiquan Zhang3 

1Oncology Department, Deyang People’s Hospital, Sichuan, People’s Republic of China; 2Nursing Department, Deyang People’s Hospital, Sichuan, People’s Republic of China; 3Nephrology Department, Deyang People’s Hospital, Sichuan, People’s Republic of China

Correspondence: Jiquan Zhang; Shaoju Xie, Deyang People’s Hospital, No. 173, Taishanbei Road, Deyang City, Sichuan Province, 618000, People’s Republic of China, Email dyzhangjiquan@163.com; 179344427@qq.com

Background: Improving the quality of life (QOL) of lung cancer patients undergoing chemotherapy is an indispensable part of cancer treatment, as it not only pertains to their physical health but also to their psychological and social well-being. Previous research has primarily focused on investigating health-related quality of life, while studies specifically addressing the QOL of lung cancer patients remain underrepresented and under researched.
Purpose: The study aims to investigate the current status of QOL among lung cancer patients and identify the predictive factors associated with QOL.
Patients and Methods: From January 2024 to June 2024, lung cancer patients undergoing chemotherapy will be recruited from the outpatient clinics or wards of a tertiary A-level hospital in Deyang City as research subjects. They will be surveyed using the general information questionnaire, the Self-rating Depression Scale (SDS), the Multidimensional Scale of Perceived Social Support (MSPSS), and the Functional Assessment of Cancer Therapy-Lung (FACT-L) scale. Multiple linear regression analysis will be employed to determine the variables associated with QOL.
Results: A total of 390 lung cancer patients undergoing chemotherapy were recruited for this study, with a male predominance accounting for 72.31%. The mean age was (59.11± 11.37) years. The overall QOL score was (66.43± 23.67). Age, family monthly income per capita, cancer clinical stage, depression, and perceived social support (PSS) were identified as independent factors influencing the QOL of lung cancer patients, accounting for 19.4% of the total variance.
Conclusion: There is still considerable room for improvement in the overall QOL of lung cancer patients undergoing chemotherapy. Based on the analysis of influencing factors, targeted and personalized intervention measures should be implemented to enhance the QOL for these patients.

Keywords: lung cancer, depression, perceived social support, quality of life, influencing factors, chemotherapy