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多模式快速康复方案对终末期肝泡型包虫病患者行离体肝切除自体肝移植术后恢复的影响:一项初步研究
Authors Qin Y, Li J, Ren Q
Received 19 January 2025
Accepted for publication 7 April 2025
Published 24 April 2025 Volume 2025:18 Pages 2039—2047
DOI http://doi.org/10.2147/IDR.S513862
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 2
Editor who approved publication: Dr Sandip Patil
Yan Qin,1 Jiafei Li,2 Qiuping Ren2,3
1Operating Room of West China Hospital/West China School of Nursing, Sichuan University, Chengdu, People’s Republic of China; 2West China School of Nursing, Sichuan University, Chengdu, People’s Republic of China; 3Division of Liver Surgery, Department of General Surgery, West China Hospital, Chengdu, People’s Republic of China
Correspondence: Qiuping Ren, Email 1076896674@qq.com
Background: While ex vivo liver resection combined with autotransplantation has been reported from various perspectives, the use of fast-track protocols for this procedure in treating end-stage hepatic alveolar echinococcosis has not been documented.
Methods: We retrospectively analyzed the outcomes of 21 patients with end-stage hepatic alveolar echinococcosis who underwent ex vivo liver resection and autotransplantation, followed by a fast-track recovery protocol at our institution between 2014 and 2017.
Results: All patients successfully underwent liver autotransplantation with no intraoperative mortality. Postoperative hospital stays ranged from 4 to 51 days, with an average of 23.5 days. Hospital costs averaged $3 million (range $1.94– 4.07 million). Twelve patients experienced postoperative complications, with four classified as Clavien-Dindo grade III or higher. Two patients died due to intra-abdominal bleeding and acute cerebral hemorrhage, respectively. Nineteen patients were followed for a median of 16.2 months (range 3– 38 months), with no recurrence of hepatic alveolar echinococcosis.
Conclusion: Fast-track protocols are safe and effective in the context of ex vivo liver resection and autotransplantation.
Keywords: fast-track surgery, autotransplantation, ex vivo resection