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    Metered Cryospray™: a novel uniform, controlled, and consistent in vivo application of liquid nitrogen cryogenic spray

     

    Authors Mulcahey TI, Coad JE, Fan WL, Grasso DJ, Hanley BM, Hawkes HV, McDermott SA, O'Connor JP, Sheets EE, Vadala CJ

    Received 7 October 2016

    Accepted for publication 15 December 2016

    Published 17 February 2017 Volume 2017:10 Pages 29—41

    DOI http://doi.org/10.2147/MDER.S124098

    Checked for plagiarism Yes

    Review by Single-blind

    Peer reviewers approved by Dr Colin Mak

    Peer reviewer comments 2

    Editor who approved publication: Dr Scott Fraser

    Abstract: In this article, a novel cryotherapy approach using a uniform, controlled, and consistent in vivo application of liquid nitrogen (LN2) spray as a Metered Cryospray™ (MCS) process is described. Although MCS may be used for many potential clinical applications, this paper focuses on the development that led to the controlled and consistent delivery of radial LN2 cryogen spray in order to generate a uniform circumferential effect and how the amount of MCS can be adapted to specifically ablate targeted diseases within a patient’s lumen such as an airway or esophagus.
    Keywords: Metered Cryospray™, cryoablation, rejuvenative healing, LN
    2 spray cryotherapy

     

    摘要视频链接:LN2 Metered Cryospray™



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